| Date | Home | Away | Result |
|---|---|---|---|
| 8/15/25 2:30 PM | Burgos CF | CyD Leonesa | 5-1 |
| 8/15/25 2:30 PM | Real Valladolid | AD Ceuta FC | 3-0 |
| 8/16/25 10:00 AM | Racing Santander | CD Castellon | 3-1 |
| 8/16/25 12:30 PM | FC Malaga | SD Eibar | 1-1 |
| 8/16/25 2:30 PM | FC Granada | Deportivo La Coruna | 1-3 |
| 8/17/25 10:00 AM | Real Sociedad B | Real Saragossa | 1-0 |
| 8/17/25 12:30 PM | FC Cadiz | CD Mirandes | 1-0 |
| 8/17/25 2:30 PM | SD Huesca | CD Leganes | 1-1 |
| 8/17/25 2:30 PM | UD Las Palmas | Andorra CF | 1-1 |
| 8/18/25 12:00 PM | Sporting Gijon | Cordoba CF | 2-1 |
| 8/18/25 2:30 PM | UD Almeria | Albacete Balompie | 4-4 |